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【Research News】Gut dysbiosis associated with hepatitis C virus infection

May 1,2018

Summary of the article's point: In hepatitis C virus infection,the progression of the clinical stage is associated with gut dysbiosis ,even if patients are asymptomatic.Overgrowth of viridans streptococci can contribute to the production of ammonia in chronic hepatitis and liver cirrhosis

gazoudata2.png

Genus composition of fecal samples from healthy individuals and chronic hepatitis C patients.

Fecal samples from healthy individuals (n=23,2sets) and chronic hepatitis C(CHC) patients diagnosed as persistently normal serum alanine aminotransferase (PNALT,n=18), chronic hepatitis
(CH, n=84),liver cirrhosis(LC,n=40),and hepatocellular carcinoma (HCC,n=24)were grouped according with the clinical stage of CHC and ordered according with Streptococcus abundance

gazoudata.png

Published online Date:May 1 , 2018

Journal:Clinical Infectious Diseases

Title Gut dysbiosis associated with hepatitis C virus infection
Author Takako Inoue, Jiro Nakayama, Kei Moriya, Hideto Kawaratani, Rie Momoda, Kiyoaki Ito, Etsuko Iio, Shunsuke Nojiri, Kei Fujiwara, Masashi Yoneda, Hitoshi Yoshiji and Yasuhito Tanaka
Article URL https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciy205/4989908?redirectedFrom=fulltext
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